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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPIL4
All Species:
26.67
Human Site:
S442
Identified Species:
41.9
UniProt:
Q8WUA2
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUA2
NP_624311.1
492
57225
S442
R
D
R
T
Q
N
R
S
R
S
R
S
R
E
R
Chimpanzee
Pan troglodytes
XP_527529
607
69328
S557
R
D
R
T
Q
N
R
S
R
S
R
S
R
E
R
Rhesus Macaque
Macaca mulatta
XP_001084421
492
57172
S442
R
D
R
T
Q
N
R
S
R
S
R
S
R
E
R
Dog
Lupus familis
XP_541147
492
57155
S442
R
D
R
P
Q
N
R
S
R
S
R
S
R
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXG3
492
57212
S442
R
D
R
R
Q
N
R
S
R
S
R
S
R
E
R
Rat
Rattus norvegicus
NP_001101927
357
40656
D308
M
D
N
V
L
I
D
D
R
R
I
H
V
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506397
487
56623
S438
R
N
R
H
Q
S
R
S
R
S
R
S
R
D
T
Chicken
Gallus gallus
XP_419663
478
55881
R428
M
K
S
E
K
K
D
R
H
R
S
R
S
R
S
Frog
Xenopus laevis
Q6GLX7
477
54856
N420
A
S
D
V
D
E
E
N
D
K
G
W
L
S
H
Zebra Danio
Brachydanio rerio
NP_001121802
454
52864
S404
R
S
K
D
R
D
E
S
R
R
E
K
D
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651291
653
75452
D477
G
R
R
S
R
S
R
D
Q
K
E
R
R
R
S
Honey Bee
Apis mellifera
XP_001121334
512
60307
S435
K
H
R
D
R
S
R
S
R
S
R
D
K
S
K
Nematode Worm
Caenorhab. elegans
NP_492343
427
50388
P378
K
R
D
Y
R
R
E
P
A
R
R
R
R
S
S
Sea Urchin
Strong. purpuratus
XP_001192414
536
61906
E482
Q
G
R
G
R
G
D
E
D
R
K
R
R
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q871A4
494
56481
R439
R
D
D
R
D
N
R
R
G
P
R
D
A
D
R
Conservation
Percent
Protein Identity:
100
80.8
98.7
98.1
N.A.
96.7
71.9
N.A.
77
80.8
23.5
69.7
N.A.
42.4
48.6
47.5
51.1
Protein Similarity:
100
80.8
98.9
98.7
N.A.
98.1
72.3
N.A.
86.1
89
45.7
81
N.A.
55.9
65.8
65.6
65.4
P-Site Identity:
100
100
100
93.3
N.A.
93.3
13.3
N.A.
66.6
0
0
20
N.A.
20
40
13.3
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
20
N.A.
86.6
6.6
6.6
40
N.A.
46.6
73.3
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
43.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
60.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
0
7
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
47
20
14
14
7
20
14
14
0
0
14
7
20
7
% D
% Glu:
0
0
0
7
0
7
20
7
0
0
14
0
0
34
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
7
7
0
7
0
7
0
0
7
0
7
0
0
0
0
% G
% His:
0
7
0
7
0
0
0
0
7
0
0
7
0
0
7
% H
% Ile:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% I
% Lys:
14
7
7
0
7
7
0
0
0
14
7
7
7
7
7
% K
% Leu:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% L
% Met:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
7
0
0
40
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
7
0
0
0
7
0
7
0
0
0
0
0
% P
% Gln:
7
0
0
0
40
0
0
0
7
0
0
0
0
0
0
% Q
% Arg:
54
14
60
14
34
7
60
14
60
34
60
27
60
20
40
% R
% Ser:
0
14
7
7
0
20
0
54
0
47
7
40
7
20
27
% S
% Thr:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
7
% T
% Val:
0
0
0
14
0
0
0
0
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _